Case 1

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Here we discuss our individual patient problems through a series of inputs from an available global online community of experts to solve those patients' clinical problems with collective current best evidence-based inputs.


Date of admission- 16/08/2021

A 70-year-old man, who is a farm worker by occupation, presented to the hospital with

- Pain in the epigastric region since 4 days

- Constipation since 4 days

- Burning micturition since 10 days 

- Decreased urine output since 10 days 

- Shortness of breath and swelling in feet since 1 month

- Backpain and fever since 2 months



HISTORY OF PRESENT ILLNESS

- Patient was apparently asymptomatic 4 years ago and then developed cough, fever, swelling in the legs for which he visited a local hospital where he was diagnosed with Chronic Renal Failure

- Referred to current hospital for treatment for CRF 4 years ago and was on medication for 1 year which he discontinued after his symptoms got better
- Patient had pain in the back 3 years ago which subsided on taking painkillers prescribed by local RMP

- His attendant has mentioned that the patient took the same painkillers liberally over the past 2 years whenever he felt pain in the back

- Patient continued his smoking and drinking habit 3 months ago

- Backpain and fever since 2 months

- 1 month ago, he started experiencing shortness of breath, cough with sputum and pedal edema

- Burning micturition and decreased urine output since 10 days

- Pain in the epigastric region since 4 days



PAST HISTORY

- Known case of hypertension since 1 year

- Patient is a known case of Chronic Renal Failure since 4 years 

- Patient was suffering from Tuberculosis infection 20 years ago 

- Not a known case of Diabetes mellitus, Asthma, Epilepsy


PERSONAL HISTORY

-Mixed diet of veg and non-veg food

-Appetite Inadequate

-Bowel movements- decreased- once in 2-3 days

-Decreased urine output with burning micturition since 10 days

-Patient is an alcoholic since the age of 20 years 

-Chronic smoker (4-5 chutta/day) since the age of 15 years 

-Patient stopped smoking and drinking 4 years ago 

-Patient started drinking and smoking again 3 months ago


TREATMENT HISTORY

-Patient is on antihypertensives since 1 year

-Patient took painkillers liberally over the span of 2 years whenever he felt pain and discomfort especially in the neck and back area


GENERAL EXAMINATION
- Patient is conscious, coherent and cooperative
- Pallor- Yes
- Cyanosis- No
- Lymphadenopathy- No
- Clubbing of fingers- No
- Bipedal pitting edema

     
Shape of abdomen- Scaphoid
No tenderness



Vitals
Temperature- 98.6 F
Pulse rate- 82 BPM
S1 and S2 heard
spO2- 94
BP- 120/70
S1 and S2 heard 


PROVISIONAL DIAGNOSIS
Chronic Renal Failure (?Analgesic Nephropathy)
?COPD
?Viral Thrombocytopenia


INVESTIGATIONS

16/08/2021



17/08/2021





18/08/2021







19/08/2021




20/08/2021



FEVER CHART


ULTRASOUND

ECG




TREATMENT

DAY 1

Fluid retention <2L/day

Salt retention <2L/day

INJ Lasix 40mg/ IV TID

TAB Nodosis 500mg/PO/TID

TAB Shelcal 500mg/PO/OD

TAB Amlong 5mg/PO/OD

TAB Orofer- XT PO/OD

Neb Duolin- 8th hourly

Neb Budecor- 12th hourly

Strict I/O charting

GRBS 8th hourly

Monitor vitals 8th hourly


DAY 2

INJ Lasix 40mg/ IV TID

TAB Nodosis 500mg/PO/TID

TAB Shelcal 500mg/PO/OD

TAB Amlong 5mg/PO/OD

TAB Orofer- XT PO/OD

Neb Duolin- 8th hourly

Neb Budecor- 12th hourly

Strict I/O charting

GRBS 8th hourly

Monitor vitals 8th hourly

DAY 3

Haemodialysis for 2 hours 

INJ Tranexa 1amp/ IV/ STAT

INJ NaHCO3 100 meq in 200ml NS/IV/STAT

INJ 3% NaCl infusion at 10ml/hr for 4 hours

Fluid retention <1.5 L/day

DAY 4

Fluid retention <1.5 L/day

INJ Lasix 40mg/ IV TID

NJ Ceftriaxone 1g/IV/BD

INJ Pan 40mg/ IV/OD

TAB Nodosis 500mg/PO/TID

TAB Orofer- XT PO/OD

TAB Amlong 5mg/PO/OD

Neb Ipravent- 8th hourly

DAY 5

Fluid retention <1.5 L/day

INJ Ceftriaxone 1g/IV/BD

INJ Pan 40mg/ IV/OD

TAB Nodosis 500mg/PO/TID

TAB Orofer- XT PO/OD

TAB Amlong 5mg/PO/OD

Neb Ipravent- 8th hourly

Neb Budecor- 12th hourly

GRBS 8th hourly

Monitor vitals 4th hourly

DISCUSSION


1) What could be the possible reason for patient's kidney failure and probable COPD?

2) What is the effect of chronic abuse of NSAIDs on kidneys?

3) What could be the probable cause of thrombocytopenia in this case? 









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